Science Talk - Paul Burstow MP visits the Institute for Cancer Research



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Paul Burstow MP visiting Maria Vinci and Sue Eccles in May 2013

Paul Burstow, MP for Sutton and Cheam, meets with ICR researchers Dr. Maria Vinci and Dr. Sue Eccles
Last week Paul Burstow, Sutton and Cheam Liberal Democrat MP and former Minister of Health, visited us on the Sutton campus right here on the Institute of Cancer Research in London.

Part of my job is to get politicians and decision-makers smitten by our work, and there may be hardly a greater approach to do that than to satisfy MPs with our scientists in individual.

On this event, Mr. Burstow's go to was motivated by the need to have one among our postdocs right here on the Institute for Cancer Research (ICR), Dr. Maria Vinci, to satisfy. Earlier this 12 months, Dr. Vinci chosen from a whole lot of biomedical science researchers to do their work within the House of Commons underneath the SET for Great Britain. The competitors invitations younger lecturers from throughout the UK to explain their work in a approach that's accessible to non-academics. Every 12 months the very best contributors are chosen to current a poster of their work to politicians and a jury of specialists within the House of Commons in March.

Paul Burstow was unable to attend this occasion and as a substitute visited Dr. Vinci in our laboratories on the ICR to seek out out extra about her work. Mr. Burstow met with Dr. Vinci and ICR staff chief Dr. Sue Eccles to seek out out extra about her challenge that was carried out by. was funded The National Center for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs).

Dr. Vinci has developed a brand new technique for rising 3D micro-cancer. In distinction to conventional laboratory analysis strategies, wherein most cancers cells are grown as flat plates in dishes, this technique of cell cultivation permits us to extra precisely mannequin what's going on inside a tumor. These micro-cancers exhibit shut inter-cellular interactions, as would happen in tumors, and even essential hallmarks of malignancy, equivalent to the flexibility of the cells to maneuver and penetrate tissues and acquire their very own blood provide from the host tissue.

Dr. Vinci can concurrently develop and analyze 96 of those micro-cancers on a postcard-sized plate and monitor their progress in actual time utilizing automated imaging strategies. With this extra related mannequin, we will check potential most cancers medication and observe their therapeutic results in a extra thorough cell system earlier than shifting to later levels of the drug growth course of. In addition, by excluding medication which can be ineffective, we will cut back the variety of animals wanted for analysis earlier.

When I received to Dr. When Vinci requested concerning the competitors, she mentioned, “I utilized to SET for BRITAIN as a result of it is an awesome alternative to advertise my work on the ICR. I hope that the assembly with MPs will make politicians increasingly conscious of the significance of getting their assist in order that the nation can lead new scientific discoveries. "

During the visit, Mr. Burstow also met with the ICR's Deputy General Manager Professor Paul Workman to discuss the wider work of the ICR. As you might imagine from a former health minister, Mr. Burstow seemed very preoccupied with medical research and asked a number of questions about our research and the way we work. He was particularly interested in our collaboration with hospitals and industry, the clinical studies we conducted, and the commercial impact of our drug discovery.

Working in partnership is the key to transferring our research results into a clinical setting. Professor Workman described our close relationship with partner hospital The Royal Marsden NHS Foundation Trust and highlighted national programs to support our translational approach, such as: NIHR Biomedical Research Centers, Centers for Experimental Cancer Medicine and Cancer Research UK Cancer Centers. These allow us to work with companions and donors to advance most cancers analysis.

Professor Workman additionally described the best way we work with pharmaceutical corporations. Some of our discoveries end in mental property that may be exploited commercially - so we will channel the entire income again into our analysis for additional affected person profit.

If important investments are required to comprehend the affected person good thing about our analysis, we will license our discoveries to an industrial associate. This advantages the ICR because it offers us entry to sources and abilities outdoors of the group and ensures that our discoveries are quickly developed for scientific profit. In return, our early-stage analysis takes a threat that is probably not acceptable to a pharmaceutical firm that should make a revenue for its shareholders.

These forms of conversations permit us to speak not solely concerning the analysis we're doing right here and the way it's resulting in improved outcomes for most cancers sufferers, but additionally about how analysis is being carried out. As Maria mentioned, we'd like assist if we would like the nation to cleared the path in new scientific discoveries and talk about the type of setting we'd like.

This go to from our native MP gave us a chance to speak about how we should always construct a analysis setting wherein we will work collectively to realize our targets sooner. Participation in competitions equivalent to SET for Britain or different applications the place scientists meet MPs offers us the chance not solely to current the thrilling analysis right here on the ICR, but additionally to advertise science normally.

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